The Inheritance: A Family on the Front Lines of the Battle Against Alzheimer's Disease
(Adobe EPUB eBook, Kindle Book, OverDrive Read)
Every sixty-nine seconds, someone is diagnosed with Alzheimer's disease. Of the top ten killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can.
The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer's, an inherited genetic mutation that causes the disease in one hundred percent of cases, and has a fifty percent chance of being passed onto the next generation. Of the six DeMoe children whose father had it, five have inherited the gene; the sixth, daughter Karla, has inherited responsibility for all of them. But rather than give up in the face of such news, the DeMoes have agreed to spend their precious, abbreviated years as part of a worldwide study that could utterly change the landscape of Alzheimer's research and offers the brightest hope for future treatments—and possibly a cure.
Drawing from several years of in-depth research with this charming and upbeat family, journalist Niki Kapsambelis tells the story of Alzheimer's through the humanizing lens of these ordinary people made extraordinary by both their terrible circumstances and their bravery. "A compelling narrative...and an educational and emotional chronicle" (Kirkus Reviews, starred review), their tale is intertwined with the dramatic narrative history of the disease, the cutting-edge research that brings us ever closer to a possible cure, and the accounts of the extraordinary doctors spearheading these groundbreaking studies. From the oil fields of North Dakota to the jungles of Colombia, this inspiring race against time redefines courage in the face of this most pervasive and mysterious disease.
If you are having problem transferring a title to your device, please fill out this support form or visit the library so we can help you to use our eBooks and eAudio Books.
Niki Kapsambelis. (2017). The Inheritance: A Family on the Front Lines of the Battle Against Alzheimer's Disease. Simon & Schuster.
Chicago / Turabian - Author Date Citation (style guide)Niki Kapsambelis. 2017. The Inheritance: A Family On the Front Lines of the Battle Against Alzheimer's Disease. Simon & Schuster.
Chicago / Turabian - Humanities Citation (style guide)Niki Kapsambelis, The Inheritance: A Family On the Front Lines of the Battle Against Alzheimer's Disease. Simon & Schuster, 2017.
MLA Citation (style guide)Niki Kapsambelis. The Inheritance: A Family On the Front Lines of the Battle Against Alzheimer's Disease. Simon & Schuster, 2017.
| Library | Owned | Available |
|---|---|---|
| Shared Digital Collection | 1 | 0 |
OverDrive Product Record
- images
- cover:
- href: https://img1.od-cdn.com/ImageType-100/0439-1/{D04E1D8C-EDE0-49B8-A9E4-D5BAD664EC1F}Img100.jpg
- type: image/jpeg
- thumbnail:
- href: https://img1.od-cdn.com/ImageType-200/0439-1/{D04E1D8C-EDE0-49B8-A9E4-D5BAD664EC1F}Img200.jpg
- type: image/jpeg
- cover150Wide:
- href: https://img1.od-cdn.com/ImageType-150/0439-1/D04/E1D/8C/{D04E1D8C-EDE0-49B8-A9E4-D5BAD664EC1F}Img150.jpg
- type: image/jpeg
- cover300Wide:
- href: https://img1.od-cdn.com/ImageType-400/0439-1/D04/E1D/8C/{D04E1D8C-EDE0-49B8-A9E4-D5BAD664EC1F}Img400.jpg
- type: image/jpeg
- cover:
- formats
- identifiers:
- type: ISBN
- value: 9781451697339
- name: Adobe EPUB eBook
- id: ebook-epub-adobe
- identifiers:
- identifiers:
- type: ASIN
- value: B01HMXV20Y
- name: Kindle Book
- id: ebook-kindle
- identifiers:
- identifiers:
- type: ISBN
- value: 9781451697339
- name: OverDrive Read
- id: ebook-overdrive
- identifiers:
- mediaType
- eBook
- primaryCreator
- role: Author
- name: Niki Kapsambelis
- title
- The Inheritance
- dateAdded
- 2017-03-03T11:52:00-05:00
- contentDetails
- href: https://link.overdrive.com/?websiteID=141&titleID=2831212
- type: text/html
- account:
- name: Sacramento Public Library (CA)
- id: 1151
- sortTitle
- Inheritance A Family on the Front Lines of the Battle Against Alzheimers Disease
- crossRefId
- 2831212
- subtitle
- A Family on the Front Lines of the Battle Against Alzheimer's Disease
- id
- d04e1d8c-ede0-49b8-a9e4-d5bad664ec1f
- starRating
- 4.3
OverDrive MetaData
- isPublicDomain
- False
- formats
- fileName: TheInheritance_9781451697339_2831212
- partCount: 0
- fileSize: 13911749
- identifiers:
- type: ISBN
- value: 9781451697339
- rights:
- type: Copying
- value: 0
- type: Printing
- value: 0
- type: Lending
- value: 0
- type: ReadAloud
- value: 0
- type: ExpirationRights
- value: 0
- name: Adobe EPUB eBook
- isReadAlong: False
- id: ebook-epub-adobe
- onSaleDate: 3/7/2017
- samples:
- source: From the book
- formatType: ebook-overdrive
- url: https://samples.overdrive.com/?crid=d04e1d8c-ede0-49b8-a9e4-d5bad664ec1f&.epub-sample.overdrive.com
- fileName: TheInheritance_2831212
- partCount: 0
- fileSize: 0
- identifiers:
- type: ASIN
- value: B01HMXV20Y
- name: Kindle Book
- isReadAlong: False
- id: ebook-kindle
- onSaleDate: 3/7/2017
- samples:
- source: From the book
- formatType: ebook-overdrive
- url: https://samples.overdrive.com/?crid=d04e1d8c-ede0-49b8-a9e4-d5bad664ec1f&.epub-sample.overdrive.com
- fileName: TheInheritance_9781451697339_2831212
- partCount: 0
- fileSize: 13911714
- identifiers:
- type: ISBN
- value: 9781451697339
- name: OverDrive Read
- isReadAlong: False
- id: ebook-overdrive
- onSaleDate: 3/7/2017
- samples:
- source: From the book
- formatType: ebook-overdrive
- url: https://samples.overdrive.com/?crid=d04e1d8c-ede0-49b8-a9e4-d5bad664ec1f&.epub-sample.overdrive.com
- keywords
- value: pittsburgh
- value: concussion
- value: research
- value: Los Angeles Times
- value: Big Pharma
- value: fox
- value: nhs
- value: Genome
- value: Alzheimer's
- value: PIB
- value: Pennsylvania
- value: Doctor
- value: Colombia
- value: people
- value: inspiring
- value: North Dakota
- value: Associated Press
- value: Medicine
- value: courage
- value: Genetics
- value: Baby Boomers
- value: Alzheimer's Disease
- value: memory loss
- value: Washington Post
- value: FDA
- value: Dian
- value: genetic mutation
- value: lisa genova
- value: still alice
- value: new york daily news
- value: entertainment weekly
- value: Kirkus
- value: booklist
- value: early onset alzheimer's
- value: alzheimer's cure
- value: The Inheritance
- value: brain on fire
- value: susannah cahalan
- value: Immortal Life of Henrietta Lacks
- value: knocking on heaven's door
- value: David Shenk
- value: the forgetting
- value: kirkus reviews
- value: katy butler
- value: god's hotel
- value: bill clunk
- value: chet mathis
- value: jeanne marie laskas
- value: kathleen gallagher
- value: niki kapsambelis
- value: one in a billion
- value: pittsburgh compound b
- value: preventative treatment
- value: victoria sweet
- value: we are not ourselves
- value: when the spirit catches you and you fall down
- creators
- role: Author
- fileAs: Kapsambelis, Niki
- bioText: Niki Kapsambelis was born and raised in Boston, Massachusetts. She worked for several years as a newswoman for the Associated Press in New England, Los Angeles, and Pittsburgh. Her work has appeared in publications around the world, including The Washington Post, Los Angeles Times, and People magazine. She lives in Pennsylvania. The Inheritance is her first book.
- name: Niki Kapsambelis
- publishDate
- 2017-03-07T00:00:00-05:00
- isOwnedByCollections
- True
- title
- The Inheritance
- fullDescription
- This gripping story of the doctors at the forefront of Alzheimer's research and the courageous North Dakota family whose rare genetic code is helping to understand our most feared diseases is "excellent, accessible...A science text that reads like a mystery and treats its subjects with humanity and sympathy" (Library Journal, starred review).
Every sixty-nine seconds, someone is diagnosed with Alzheimer's disease. Of the top ten killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can.
The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer's, an inherited genetic mutation that causes the disease in one hundred percent of cases, and has a fifty percent chance of being passed onto the next generation. Of the six DeMoe children whose father had it, five have inherited the gene; the sixth, daughter Karla, has inherited responsibility for all of them. But rather than give up in the face of such news, the DeMoes have agreed to spend their precious, abbreviated years as part of a worldwide study that could utterly change the landscape of Alzheimer's research and offers the brightest hope for future treatments—and possibly a cure.
Drawing from several years of in-depth research with this charming and upbeat family, journalist Niki Kapsambelis tells the story of Alzheimer's through the humanizing lens of these ordinary people made extraordinary by both their terrible circumstances and their bravery. "A compelling narrative...and an educational and emotional chronicle" (Kirkus Reviews, starred review), their tale is intertwined with the dramatic narrative history of the disease, the cutting-edge research that brings us ever closer to a possible cure, and the accounts of the extraordinary doctors spearheading these groundbreaking studies. From the oil fields of North Dakota to the jungles of Colombia, this inspiring race against time redefines courage in the face of this most pervasive and mysterious disease. - reviews
- premium: True
- source:
- content:
Starred review from January 15, 2017
In her debut, journalist Kapsambelis builds a compelling narrative about Alzheimer's disease around one North Dakota extended family.In sections alternating among sagas of specific families, research in medical laboratories, and sweeping explanations of dementia, the author demonstrates beyond doubt that although Alzheimer's acquired its name in the early 20th century (first described by Alois Alzheimer in 1906), it has devastated human brains for thousands of years. Much of what used to pass for old-age senility has actually been virulent dementia, of which Alzheimer's is a specific type. A normal path of this abnormal disease starts with inconsistent memory, moves to the loss of motor skills, and culminates in a drawn-out, heartbreaking death phase. Alzheimer's can rip apart families, often compromising the physical and mental health of the caregivers as well as the patients. Kapsambelis focuses largely on early-onset Alzheimer's, which sometimes manifests as early as age 35. By focusing on the DeMoe family of rural North Dakota, the author was able to spend time with family members while they were still lucid. When Gail, an accomplished, lively young woman, married her husband, Galen DeMoe, she had no idea he harbored a mutant gene that would doom him and maybe any children they birthed to early-onset Alzheimer's and excruciating declines. As detection techniques to spot the specific mutant gene progressed, each of the six children born to Galen and Gail had to decide if they wanted to be tested. Some of the six wanted to know quickly, while others delayed. If they carried the mutant gene, they also had to decide if they would risk having children of their own. In addition to clear discussions of the disease's history and research, Kapsambelis successfully portrays Gail, Galen, and their extended family as fully fleshed individuals. An educational and emotional chronicle that should resonate with a wide variety of readers.COPYRIGHT(2017) Kirkus Reviews, ALL RIGHTS RESERVED.
- premium: True
- source:
- content:
November 1, 2016
Early-onset Alzheimer's results from an inherited genetic mutation that has a 50 percent chance of being passed on. Five of the DeMoes' six children inherited the gene but instead of despairing agreed to join in a worldwide study of the disease.Copyright 2016 Library Journal, LLC Used with permission.
- premium: True
- source:
- content:
March 1, 2017
Would you want to know if you were going to develop early-onset Alzheimer's disease, which would rob you of your memory and might kill you in middle age? This is the issue facing the DeMoe family of North Dakota. Journalist Kapsambelis tells the DeMoes' story and that of Alzheimer's research. The DeMoes are one of a few cohorts identified with a genetic mutation that results in a 100 percent chance of the disease in carriers and a 50 percent chance in their offspring. The author focuses on husband and wife Galen (Moe) and Gail DeMoe. Moe's mother and two of his four siblings all died of the disease, and he and Gail had six children before it was known that the disease was genetically linked. At the same time, Kapsambelis follows the pioneers of Alzheimer's research, who have carried on a tireless fight for attention and support and whose work is now promising. A science text that reads like a mystery and treats its subjects with humanity and sympathy, this volume should be of interest to everyone, as Alzheimer's is now known to be a major cause of dementia in the elderly and because we are facing a potential epidemic as the baby boom generation ages. VERDICT An excellent, accessible addition for most public libraries. [Prepub Alert 9/19/16.]--Nancy H. Fontaine, Norwich P.L., VT
Copyright 2017 Library Journal, LLC Used with permission.
- premium: True
- source:
- content:
November 1, 2016
Early-onset Alzheimer's results from an inherited genetic mutation that has a 50 percent chance of being passed on. Five of the DeMoes' six children inherited the gene but instead of despairing agreed to join in a worldwide study of the disease.
Copyright 2016 School Library Journal, LLC Used with permission.
- popularity
- 221
- links
- self:
- href: https://api.overdrive.com/v1/collections/v1L1BWwAAAA2I/products/d04e1d8c-ede0-49b8-a9e4-d5bad664ec1f/metadata
- type: application/vnd.overdrive.api+json
- self:
- id
- d04e1d8c-ede0-49b8-a9e4-d5bad664ec1f
- starRating
- 4.3
- images
- cover:
- href: https://img1.od-cdn.com/ImageType-100/0439-1/{D04E1D8C-EDE0-49B8-A9E4-D5BAD664EC1F}Img100.jpg
- type: image/jpeg
- thumbnail:
- href: https://img1.od-cdn.com/ImageType-200/0439-1/{D04E1D8C-EDE0-49B8-A9E4-D5BAD664EC1F}Img200.jpg
- type: image/jpeg
- cover150Wide:
- href: https://img1.od-cdn.com/ImageType-150/0439-1/D04/E1D/8C/{D04E1D8C-EDE0-49B8-A9E4-D5BAD664EC1F}Img150.jpg
- type: image/jpeg
- cover300Wide:
- href: https://img1.od-cdn.com/ImageType-400/0439-1/D04/E1D/8C/{D04E1D8C-EDE0-49B8-A9E4-D5BAD664EC1F}Img400.jpg
- type: image/jpeg
- cover:
- isPublicPerformanceAllowed
- False
- languages
- code: en
- name: English
- subjects
- value: Biography & Autobiography
- value: Medical
- value: Science
- value: Nonfiction
- publishDateText
- 03/07/2017
- otherFormatIdentifiers
- type: ISBN
- value: 9781451697322
- mediaType
- eBook
- shortDescription
- This gripping story of the doctors at the forefront of Alzheimer's research and the courageous North Dakota family whose rare genetic code is helping to understand our most feared diseases is "excellent, accessible...A science text that reads like a mystery and treats its subjects with humanity and sympathy" (Library Journal, starred review).
Every sixty-nine seconds, someone is diagnosed with Alzheimer's disease. Of the top ten killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can.
The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer's, an inherited genetic mutation that causes the disease in one hundred percent of cases, and has a fifty percent chance of being passed onto the next generation. Of the six DeMoe children whose father had it, five have inherited the gene; the sixth, daughter... - sortTitle
- Inheritance A Family on the Front Lines of the Battle Against Alzheimers Disease
- crossRefId
- 2831212
- subtitle
- A Family on the Front Lines of the Battle Against Alzheimer's Disease
- publisher
- Simon & Schuster
- bisacCodes
- code: BIO017000
- description: Biography & Autobiography / Medical
- code: MED056000
- description: Medical / Neurology
- code: SCI029000
- description: Science / Life Sciences / Genetics & Genomics
