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Miracle Cure: The Creation of Antibiotics and the Birth of Modern Medicine
(Adobe EPUB eBook, Kindle Book, OverDrive Read)

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Penguin Publishing Group 2017
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Description
The epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma.
As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.
     William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born.
    Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.
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Format:
Adobe EPUB eBook, Kindle Book, OverDrive Read
Street Date:
05/09/2017
Language:
English
ISBN:
9780698184107
ASIN:
B01KGZVQ2E
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Citations
APA Citation (style guide)

William Rosen. (2017). Miracle Cure: The Creation of Antibiotics and the Birth of Modern Medicine. Penguin Publishing Group.

Chicago / Turabian - Author Date Citation (style guide)

William Rosen. 2017. Miracle Cure: The Creation of Antibiotics and the Birth of Modern Medicine. Penguin Publishing Group.

Chicago / Turabian - Humanities Citation (style guide)

William Rosen, Miracle Cure: The Creation of Antibiotics and the Birth of Modern Medicine. Penguin Publishing Group, 2017.

MLA Citation (style guide)

William Rosen. Miracle Cure: The Creation of Antibiotics and the Birth of Modern Medicine. Penguin Publishing Group, 2017. Web.

Note! Citation formats are based on standards as of July 2010. Citations contain only title, author, edition, publisher, and year published. Citations should be used as a guideline and should be double checked for accuracy.
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Date Added:
Jun 12, 2018 18:23:40
Date Updated:
Dec 06, 2020 02:46:58
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title
Miracle Cure
fullDescription
The epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma.
As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.
     William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born.
    Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.
reviews
      • premium: True
      • source: Publisher's Weekly
      • content:

        Starred review from March 13, 2017
        Former publisher and editor Rosen (The Third Horseman) tackles a dazzling chapter of modern medical history in this chronicle of the discoveries that opened the age of antibiotics and gave humankind its first effective tool to fight back in an “eons-long war” with infectious disease. It was a breathtaking leap of innovation. Rosen deftly recounts the early work of such pioneers as Louis Pasteur, who established the germ theory; Robert Koch, who linked a microorganism to a single disease; Paul Ehrlich, producer of the world’s first synthetic chemotherapeutic agent; Gerhard Domagk, whose lab found the first successful antibacterial drug; and Alexander Fleming, the man who discovered penicillin. Rosen posits that 19th- and 20th-century scientists’ most enduring contributions might have been institutional, in the forms of biological laboratory development and massive corporate funding from such giants as Merck, Pfizer, and Squibb that fueled the revolution in medicine. “Every triumphal discovery” in the dawning age of antibiotics, Rosen eloquently notes, “has been followed, sometimes in a matter of months, by a reminder that the enemy in this particular war may lose individual battles, but that the war against it is essentially eternal.” Rosen’s thoughtful, scholarly, and engaging history is a powerful testament to this fight. Agent: Eric Simonoff, WME.

      • premium: True
      • source: Kirkus
      • content:

        Starred review from March 15, 2017
        A richly documented history of the rise--and threatened future--of antibiotics.Before the invention of antibiotics, doctors practiced -heroic medicine,- rebalancing the body's humors with bloodletting, blistering, purges, enemas, and other primitive techniques. But in the late 1800s came Louis Pasteur and Robert Koch, and suddenly the world knew that cholera, plague, tuberculosis, diphtheria, and other maladies were caused by invisible microbes: bacteria. So began the hunt for remedies. There were some successes--antitoxin for diphtheria, a vaccine for anthrax--but competition and venomous rivalries prevailed, pitting Pasteur against Koch, France against Germany. Rosen's (The Third Horseman: Climate Change and the Great Famine of the 14th Century, 2014, etc.) warts-and-all sketches of the key figures serve as refreshing antidotes to the hero-worship texts we read as schoolchildren. The author also deftly contrasts Germany's synthetic dye industry, which funded research that led to Paul Ehrlich's Salvarsan for syphilis, with the feeble research support elsewhere. But the real revolution in remedies had to wait until World War II and the rediscovery of penicillin, when British scientists came to America for help in the fermentation process needed to generate copious amounts of the extract. Then came Selman Waksman, who coined the word -antibiotic- and found in a soil sample a bacterial strain that produced its own antibacterial product that worked against TB. The race was on for other useful soil microbes, and numerous drug companies emerged (and merged), from small producers of herbals and botanicals to big-time generators of lucrative broad-spectrum antibiotics. Rosen also charts the course of the FDA and the development of testing and safety protocols. Unfortunately, the current scene is ominous. Antibiotic resistance is serious and continues to grow thanks to low dosages of antibiotics still allowed in animal feeds. Rosen offers some hope regarding new approaches to combat resistance, but they seem meager. An encyclopedic reference for researchers and practitioners but also accessible for general readers due to Rosen's lively depiction of the people, places, and politics that color the history of the fight against infectious disease.

        COPYRIGHT(2017) Kirkus Reviews, ALL RIGHTS RESERVED.

      • premium: True
      • source: Library Journal
      • content:

        January 1, 2017
        The discovery of penicillin not only changed the relationship between humans and disease but, explains Rosen (The Third Horseman), required massive trial-and-error experimentation and hence massive funding, leading to Big Pharma.

        Copyright 2017 Library Journal, LLC Used with permission.

popularity
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shortDescription
The epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma.
As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.
     William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and...
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