Beyond the skyline of Toledo stands the Toledo Institute of Astronomy, the nation's premier center of astronomical discovery and a beacon of scientific learning for astronomers far and wide. One of these is George Dermont, a dreamer and a man of deep faith, who's trying to prove the scientific existence of a Gateway to God, and speaks to ancient gods and believes they speak back. Irene Sparks is a pragmatist and mathematician invited to lead the Institute's work on a massive superconductor being constructed below Toledo. This would be a scientist's dream come true, but it's particularly poignant for Irene who has been in self-imposed exile from Toledo and her estranged alcoholic mother, Bernice. When Bernice dies unexpectedly, Irene resolves to return to Toledo, and sets in motion a series of events which place George and Irene on a collision course with love, destiny and fate. George and Irene were born to be together. Their mothers, friends since childhood, hatched a plan to get pregnant together, raise the children together and then separate them so as to become each other's soulmates as adults. Can true love exist if engineered from birth?